This is an approximate time frame for lecture topics and reading assignments
that accompany each topic. The exam dates will not change.
| Date | Day | Topic | Assigned reading
in Gilbert |
| 8/30 | Mon. | Course Information/Intro to Development | pp. 1-12 |
| 9/1 | Wed. | Unicellular Developmental Model Organisms | pp. 12-28 |
| 9/3 | Fri. | Evolution of Development/Model systems | pp. 28-34 |
| 9/6 | Mon. | Basic Concepts I-Differential Gene Expression | pp. 40-54 |
| 9/8 | Wed. | Transcriptional Regulation | pp. 391-409,415-430 |
| 9/10 | Fri. | Topic #1 Animal cloning | paper handout |
| 9/13 | Mon. | Basic Concepts II-Differential Cell Affinity | pp. 79-106 |
| 9/15 | Wed. | Cell Signalling | pp. 107-120 |
| 9/17 | Fri. | Topic #2-Signalling pathways | paper handout |
| 9/20 | Mon. | Fertilization | pp. 121-139 |
| 9/22 | Wed. | Fertilization (cont) | pp. 139-166 |
| 9/24 | Fri. | Topic #3 Fertilization | paper handout |
| 9/27 | Mon. | discussion with speaker | |
| 9/29 | Wed. | Cleavage | pp. 167-196 |
| 10/1 | Fri. | Cleavage-Mechanisms | pp. 196-208 |
| 10/4 | Mon. | Exam I- covers material to 10/1 | |
| 10/6 | Wed. | Intro to Terratogenesis-Independent Projects | |
| 10/8 | Fri. | Gastrulation-Sea Urchin | pp. 209-221 |
| 10/11 | Mon. | Fall recess | |
| 10/13 | Wed. | Gastrulation-Amphibians | pp. 221-233, 606-621 |
| 10/15 | Fri. | Gastrulation- Chick | pp. 233-252 |
| 10/18 | Mon. | Gastrulation-Mammals | |
| 10/20 | Wed. | Neurulation | pp. 253-276 |
| 10/22 | Fri. | Topic #4 fate mapping | paper handout |
| 10/25 | Mon. | Neural development | pp. 276-306 |
| 10/27 | Wed. | Neural/ectoderm development | pp. 313-338 |
| 10/29 | Fri. | Topic #5 Organogenesis | paper handout |
| 11/1 | Mon. | Mesoderm Development | pp. 341-358 |
| 11/3 | Wed. | Mesodermal Development | pp. 358-366 |
| 11/5 | Fri. | Endoderm Development | pp.366-380 |
| 11/8 | Mon. | Exam II-covers lecture material from 10/2 to 11/1 | |
| 11/10 | Wed. | Cell specification by Cytoplasm Determinants | pp. 505-542 |
| 11/12 | Fri. | Morphogenesis/Axis Specification in Drosophila | pp. 543-569 |
| 11/15 | Mon. | Axis Specification in Drosophila/A-P axis | pp. 569-577 |
| 11/17 | Wed. | A-P axis in Mammals | pp. 635-650 |
| 11/19 | Fri. | Topic #6 Evolution of axis formation | paper handout |
| 11/22 | Mon. | Homeobox and Evolution | |
| 11/24 | Wed. | Thanksgiving Recess | |
| 11/26 | Fri. | Thanksgiving Recess | |
| 11/29 | Mon. | Cell Specification by Cell Interactions | pp. 591-606 |
| 12/1 | Wed. | Proximate tissue interactions-a look back | pp. 655-672 |
| 12/3 | Fri. | Topic #8 Cell Interactions | paper handout |
| 12/6 | Mon. | Limb development | pp. 701-721 |
| 12/8 | Wed. | Limb development | pp. 721-732 |
| 12/10 | Fri. | overview/review |
The final exam will be given as scheduled during the final exam period 12/15-22. The final exam will cover material presented in the lectures from 11/8 through 12/10 (80% or so of the final exam) and some questions of a more comprehensive nature (20% of the final exam).
Provisional Lab Schedule
Fall 1998
Since we are working in large part with living organisms, this schedule is tentative. Animals donít always conform to schedules. I will let you know as far in advance as possible if there is a change in this schedule, but donít be surprised if there is a change in experiments or organisms.
week 1 8/30-9/1 No Lab
week 2 9/8-10 Microscopy/Slime Mold
week 3 9/13-15 Gametogenesis
week 4 9/20-22 Sea Urchin I-Fertilization and
Cleavage
week 5 9/27-29 Sea Urchin II-Perturbing the
Embryo/Computer Modeling
week 6 10/4-10/6 Frog Early Development
10/8 Turn in Notebook
for evaluation of labs through 9/30
week 7 10/11-12 Fall recess-no labs, Lab will
be open and I will be available on Wed, 10/14 for makeup and independent
project discussions
week 8 10/18-20 Chick I --Live embryos, Discuss
Independent Project
10/22 Independent Project Proposal Due
week 9 10/25-27 Chick II-Prepared slides, Discuss
Independent Projects
week 10 11/1-3 Chick terratogenesis Independent Projects-injections
week 11 11/8-10 Independent Projects-initial assessment
and fixation
week 12 11/15-17 Independent Projects-continued assessment
week 13 11/22-24 No lab-Thanksgiving Recess, Lab
will be open and I will be available on Tues, 11/25 for makeup, independent
project work and questions
week 14 11/29-12/1 Independent Project Presentation
week 15 12/6-8 Drosophila gene expression
12/10 Turn
in Notebooks for evaluation
Important Dates
in Lecture
Examination I 10/4
Examination II 11/8
Examination III 12/14-21
in Lab
Notebooks Turned In 10/8
Discuss Independent Projects 10/18-20, 10/25-27
Proposals Due 10/22
Independent Projects 11/1 through 11/17
Presentations 11/29-12/1
Notebooks Turned In 12/10